2oj2: Difference between revisions

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[[Image:2oj2.gif|left|200px]]<br /><applet load="2oj2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2oj2.gif|left|200px]]
caption="2oj2" />
 
'''NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1)'''<br />
{{Structure
|PDB= 2oj2 |SIZE=350|CAPTION= <scene name='initialview01'>2oj2</scene>
|SITE=
|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= HCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OJ2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ACE:'>ACE</scene> and <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2A4Y. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OJ2 OCA].  
2OJ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2A4Y. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OJ2 OCA].  


==Reference==
==Reference==
Solution structure of a Hck SH3 domain ligand complex reveals novel interaction modes., Schmidt H, Hoffmann S, Tran T, Stoldt M, Stangler T, Wiesehan K, Willbold D, J Mol Biol. 2007 Feb 2;365(5):1517-32. Epub 2006 Nov 10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17141806 17141806]
Solution structure of a Hck SH3 domain ligand complex reveals novel interaction modes., Schmidt H, Hoffmann S, Tran T, Stoldt M, Stangler T, Wiesehan K, Willbold D, J Mol Biol. 2007 Feb 2;365(5):1517-32. Epub 2006 Nov 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17141806 17141806]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: human hck; sh3; src-type tyrosine kinase; nmr]]
[[Category: human hck; sh3; src-type tyrosine kinase; nmr]]


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