2oiq: Difference between revisions

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-[[Image:2oiq.gif|left|200px]]<br /><applet load="2oiq" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2oiq.gif|left|200px]]
-caption="2oiq, resolution 2.07&Aring;" />
-'''Crystal Structure of chicken c-Src kinase domain in complex with the cancer drug imatinib.'''<br />
+ {{Structure
+|PDB= 2oiq |SIZE=350|CAPTION= <scene name='initialview01'>2oiq</scene>, resolution 2.07&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=STI:4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE'>STI</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2]
+|GENE= SRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])
+}}
+'''Crystal Structure of chicken c-Src kinase domain in complex with the cancer drug imatinib.'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-OIQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=STI:'>STI</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OIQ OCA].
+OIQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OIQ OCA].
 ==Reference==
-c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty., Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J, Structure. 2007 Mar;15(3):299-311. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17355866 17355866]
+c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty., Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J, Structure. 2007 Mar;15(3):299-311. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17355866 17355866]
 [[Category: Gallus gallus]]
 [[Category: Non-specific protein-tyrosine kinase]]
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 [[Category: src]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:19:00 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:00:14 2008''