2o8d: Difference between revisions

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[[Image:2o8d.gif|left|200px]]<br /><applet load="2o8d" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2o8d.gif|left|200px]]
caption="2o8d, resolution 3.000&Aring;" />
 
'''human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair'''<br />
{{Structure
|PDB= 2o8d |SIZE=350|CAPTION= <scene name='initialview01'>2o8d</scene>, resolution 3.000&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>
|ACTIVITY=
|GENE= MSH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), MSH6, GTBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2O8D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=ADP:'>ADP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8D OCA].  
2O8D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8D OCA].  


==Reference==
==Reference==
Structure of the human MutSalpha DNA lesion recognition complex., Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS, Mol Cell. 2007 May 25;26(4):579-92. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17531815 17531815]
Structure of the human MutSalpha DNA lesion recognition complex., Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS, Mol Cell. 2007 May 25;26(4):579-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17531815 17531815]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: somatic hypermutation]]
[[Category: somatic hypermutation]]


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