2o63: Difference between revisions

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OCA

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-[[Image:2o63.gif|left|200px]]<br /><applet load="2o63" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2o63.gif|left|200px]]
-caption="2o63, resolution 2.00&Aring;" />
-'''Crystal structure of Pim1 with Myricetin'''<br />
+ {{Structure
+|PDB= 2o63 |SIZE=350|CAPTION= <scene name='initialview01'>2o63</scene>, resolution 2.00&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene> and <scene name='pdbligand=MYC:3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE'>MYC</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
+|GENE= PIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Crystal structure of Pim1 with Myricetin'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-O63 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=IMD:'>IMD</scene> and <scene name='pdbligand=MYC:'>MYC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O63 OCA].
+O63 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O63 OCA].
 ==Reference==
-Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase., Holder S, Zemskova M, Zhang C, Tabrizizad M, Bremer R, Neidigh JW, Lilly MB, Mol Cancer Ther. 2007 Jan;6(1):163-72. Epub 2007 Jan 11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17218638 17218638]
+Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase., Holder S, Zemskova M, Zhang C, Tabrizizad M, Bremer R, Neidigh JW, Lilly MB, Mol Cancer Ther. 2007 Jan;6(1):163-72. Epub 2007 Jan 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17218638 17218638]
 [[Category: Homo sapiens]]
 [[Category: Non-specific serine/threonine protein kinase]]
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 [[Category: pim1]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:14:56 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:55:35 2008''