2o4j: Difference between revisions

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[[Image:2o4j.gif|left|200px]]<br /><applet load="2o4j" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2o4j.gif|left|200px]]
caption="2o4j, resolution 1.740&Aring;" />
 
'''Crystal Structure of Rat Vitamin D Receptor Ligand Binding Domain Complexed with VitIII 17-20Z and the NR2 Box of DRIP 205'''<br />
{{Structure
|PDB= 2o4j |SIZE=350|CAPTION= <scene name='initialview01'>2o4j</scene>, resolution 1.740&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=VD4:(1R,3R,7E,17Z)-17-(5-hydroxy-1,5-dimethylhexylidene)-2-methylene-9,10-secoestra-5,7-diene-1,3-diol'>VD4</scene>
|ACTIVITY=
|GENE= Vdr, Nr1i1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''Crystal Structure of Rat Vitamin D Receptor Ligand Binding Domain Complexed with VitIII 17-20Z and the NR2 Box of DRIP 205'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2O4J is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=VD4:'>VD4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4J OCA].  
2O4J is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4J OCA].  


==Reference==
==Reference==
New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: evaluation of biological activity and structural determination of VDR-bound conformations., Vanhooke JL, Tadi BP, Benning MM, Plum LA, DeLuca HF, Arch Biochem Biophys. 2007 Apr 15;460(2):161-5. Epub 2006 Dec 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17227670 17227670]
New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: evaluation of biological activity and structural determination of VDR-bound conformations., Vanhooke JL, Tadi BP, Benning MM, Plum LA, DeLuca HF, Arch Biochem Biophys. 2007 Apr 15;460(2):161-5. Epub 2006 Dec 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17227670 17227670]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: nuclear receptor-ligand complex]]
[[Category: nuclear receptor-ligand complex]]


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