2nx3: Difference between revisions

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-[[Image:2nx3.gif|left|200px]]<br /><applet load="2nx3" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2nx3.gif|left|200px]]
-caption="2nx3, resolution 2.10&Aring;" />
-'''Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase'''<br />
+ {{Structure
+|PDB= 2nx3 |SIZE=350|CAPTION= <scene name='initialview01'>2nx3</scene>, resolution 2.10&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=A5P:ARABINOSE-5-PHOSPHATE'>A5P</scene> and <scene name='pdbligand=1NT:(2R,4R,5R,6R,7R)-2,4,5,6,7-PENTAHYDROXY-2,8-BIS(PHOSPHONOOXY)OCTANOIC ACID'>1NT</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/3-deoxy-8-phosphooctulonate_synthase 3-deoxy-8-phosphooctulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.55 2.5.1.55]
+|GENE= kdsA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])
+}}
+'''Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-NX3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=PEP:'>PEP</scene>, <scene name='pdbligand=A5P:'>A5P</scene> and <scene name='pdbligand=1NT:'>1NT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-deoxy-8-phosphooctulonate_synthase 3-deoxy-8-phosphooctulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.55 2.5.1.55] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NX3 OCA].
+NX3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NX3 OCA].
 ==Reference==
-Structural and mechanistic changes along an engineered path from metallo to nonmetallo 3-deoxy-D-manno-octulosonate 8-phosphate synthases., Kona F, Xu X, Martin P, Kuzmic P, Gatti DL, Biochemistry. 2007 Apr 17;46(15):4532-44. Epub 2007 Mar 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17381075 17381075]
+Structural and mechanistic changes along an engineered path from metallo to nonmetallo 3-deoxy-D-manno-octulosonate 8-phosphate synthases., Kona F, Xu X, Martin P, Kuzmic P, Gatti DL, Biochemistry. 2007 Apr 17;46(15):4532-44. Epub 2007 Mar 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17381075 17381075]
 [[Category: 3-deoxy-8-phosphooctulonate synthase]]
 [[Category: Aquifex aeolicus]]
@@ Line 25: / Line 34: @@
 [[Category: kdo]]
 [[Category: kdo8p]]
-[[Category: kdo8ps]]
+[[Category: kdo8p]]
 [[Category: pep]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:12:00 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:52:14 2008''