2ph5: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ph5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PH5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ph5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PH5 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hss, lpg2495 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 Legionella pneumophila subsp. pneumophila str. Philadelphia 1])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hss, lpg2495 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 Legionella pneumophila subsp. pneumophila str. Philadelphia 1])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Homospermidine_synthase Homospermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.44 2.5.1.44] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Homospermidine_synthase Homospermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.44 2.5.1.44] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ph5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ph5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ph5 RCSB], [http://www.ebi.ac.uk/pdbsum/2ph5 PDBsum], [http://www.topsan.org/Proteins/NESGC/2ph5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ph5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ph5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ph5 RCSB], [http://www.ebi.ac.uk/pdbsum/2ph5 PDBsum], [http://www.topsan.org/Proteins/NESGC/2ph5 TOPSAN]</span></td></tr>
<table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Homospermidine synthase]]
[[Category: Homospermidine synthase]]
[[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]]
[[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]]
[[Category: Acton, T B.]]
[[Category: Acton, T B]]
[[Category: Baran, M C.]]
[[Category: Baran, M C]]
[[Category: Cunningham, K.]]
[[Category: Cunningham, K]]
[[Category: Fang, Y.]]
[[Category: Fang, Y]]
[[Category: Forouhar, F.]]
[[Category: Forouhar, F]]
[[Category: Hunt, J F.]]
[[Category: Hunt, J F]]
[[Category: Hussain, M.]]
[[Category: Hussain, M]]
[[Category: Janjua, H.]]
[[Category: Janjua, H]]
[[Category: Liu, J.]]
[[Category: Liu, J]]
[[Category: Ma, L-C.]]
[[Category: Ma, L-C]]
[[Category: Montelione, G T.]]
[[Category: Montelione, G T]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Owens, L.]]
[[Category: Owens, L]]
[[Category: Seetharaman, J.]]
[[Category: Seetharaman, J]]
[[Category: Tong, L.]]
[[Category: Tong, L]]
[[Category: Xiao, R.]]
[[Category: Xiao, R]]
[[Category: Alpha-beta protein]]
[[Category: Alpha-beta protein]]
[[Category: Nesg]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: PSI, Protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 16:46, 19 January 2015

Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54

Structural highlights

2ph5 is a 1 chain structure with sequence from Legionella pneumophila subsp. pneumophila str. philadelphia 1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Gene:hss, lpg2495 (Legionella pneumophila subsp. pneumophila str. Philadelphia 1)
Activity:Homospermidine synthase, with EC number 2.5.1.44
Resources:FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2ph5, resolution 2.50Å

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OCA