2mas: Difference between revisions

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[[Image:2mas.gif|left|200px]]<br /><applet load="2mas" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2mas.gif|left|200px]]
caption="2mas, resolution 2.3&Aring;" />
 
'''PURINE NUCLEOSIDE HYDROLASE WITH A TRANSITION STATE INHIBITOR'''<br />
{{Structure
|PDB= 2mas |SIZE=350|CAPTION= <scene name='initialview01'>2mas</scene>, resolution 2.3&Aring;
|SITE= <scene name='pdbsite=S1:Description+Not+Provided'>S1</scene>, <scene name='pdbsite=S2:Description+Not+Provided'>S2</scene>, <scene name='pdbsite=S3:Description+Not+Provided'>S3</scene> and <scene name='pdbsite=S4:Description+Not+Provided'>S4</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=PIR:2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL'>PIR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Purine_nucleosidase Purine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.1 3.2.2.1]
|GENE= IU-NH FROM C. FASCICULATA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5656 Crithidia fasciculata])
}}
 
'''PURINE NUCLEOSIDE HYDROLASE WITH A TRANSITION STATE INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2MAS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Crithidia_fasciculata Crithidia fasciculata] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=PIR:'>PIR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Purine_nucleosidase Purine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.1 3.2.2.1] Known structural/functional Sites: <scene name='pdbsite=S1:Description+Not+Provided'>S1</scene>, <scene name='pdbsite=S2:Description+Not+Provided'>S2</scene>, <scene name='pdbsite=S3:Description+Not+Provided'>S3</scene> and <scene name='pdbsite=S4:Description+Not+Provided'>S4</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MAS OCA].  
2MAS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Crithidia_fasciculata Crithidia fasciculata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MAS OCA].  


==Reference==
==Reference==
Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor., Degano M, Almo SC, Sacchettini JC, Schramm VL, Biochemistry. 1998 May 5;37(18):6277-85. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9572842 9572842]
Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor., Degano M, Almo SC, Sacchettini JC, Schramm VL, Biochemistry. 1998 May 5;37(18):6277-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9572842 9572842]
[[Category: Crithidia fasciculata]]
[[Category: Crithidia fasciculata]]
[[Category: Purine nucleosidase]]
[[Category: Purine nucleosidase]]
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[[Category: uridine]]
[[Category: uridine]]


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