2f2e: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f2e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2E FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f2e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2E FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA1607 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA1607 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f2e RCSB], [http://www.ebi.ac.uk/pdbsum/2f2e PDBsum], [http://www.topsan.org/Proteins/MCSG/2f2e TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f2e RCSB], [http://www.ebi.ac.uk/pdbsum/2f2e PDBsum], [http://www.topsan.org/Proteins/MCSG/2f2e TOPSAN]</span></td></tr>
<table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Cuff, M.]]
[[Category: Cuff, M]]
[[Category: Edwards, A.]]
[[Category: Edwards, A]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Lunin, V.]]
[[Category: Lunin, V]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Structural genomic]]
[[Category: Sanders, D A.]]
[[Category: Sanders, D A]]
[[Category: Savchenko, A.]]
[[Category: Savchenko, A]]
[[Category: Sieminska, E A.]]
[[Category: Sieminska, E A]]
[[Category: Xu, X.]]
[[Category: Xu, X]]
[[Category: Zheng, H.]]
[[Category: Zheng, H]]
[[Category: Apc5613]]
[[Category: Apc5613]]
[[Category: Dna binding protein-structural genomics complex]]
[[Category: Helix-trun-helix]]
[[Category: Helix-trun-helix]]
[[Category: Mcsg]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: PSI, Protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]

Revision as of 20:11, 15 January 2015

Crystal Structure of PA1607, a Putative Transcription FactorCrystal Structure of PA1607, a Putative Transcription Factor

Structural highlights

2f2e is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Gene:PA1607 (Pseudomonas aeruginosa)
Resources:FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The structure of the PA1607 protein from Pseudomonas aureginosa was determined at 1.85 A resolution using the Se-Met multiwavelength anomalous diffraction (MAD) technique. PA1607 forms a dimer and adopts a winged-helix motif similar to the MarR family of transcription regulators, though it has an unusual dimerization profile. The DNA-binding regions and a putative metal-binding site are not conserved in PA1607.

The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor.,Sieminska EA, Xu X, Savchenko A, Sanders DA Protein Sci. 2007 Mar;16(3):543-9. PMID:17322537[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Sieminska EA, Xu X, Savchenko A, Sanders DA. The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor. Protein Sci. 2007 Mar;16(3):543-9. PMID:17322537 doi:16/3/543

2f2e, resolution 1.85Å

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OCA