2jg4: Difference between revisions

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OCA

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-[[Image:2jg4.gif|left|200px]]<br /><applet load="2jg4" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2jg4.gif|left|200px]]
-caption="2jg4, resolution 2.80&Aring;" />
-'''SUBSTRATE-FREE IDE STRUCTURE IN ITS CLOSED CONFORMATION'''<br />
+ {{Structure
+|PDB= 2jg4 |SIZE=350|CAPTION= <scene name='initialview01'>2jg4</scene>, resolution 2.80&Aring;
+|SITE= <scene name='pdbsite=AC1:Dio+Binding+Site+For+Chain+B'>AC1</scene>
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=DIO:1,4-DIETHYLENE DIOXIDE'>DIO</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Insulysin Insulysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.56 3.4.24.56]
+|GENE=
+}}
+'''SUBSTRATE-FREE IDE STRUCTURE IN ITS CLOSED CONFORMATION'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-JG4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=DIO:'>DIO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Insulysin Insulysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.56 3.4.24.56] Known structural/functional Site: <scene name='pdbsite=AC1:Dio+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JG4 OCA].
+JG4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JG4 OCA].
 ==Reference==
-Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE., Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ, J Biol Chem. 2007 Aug 31;282(35):25453-63. Epub 2007 Jul 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17613531 17613531]
+Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE., Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ, J Biol Chem. 2007 Aug 31;282(35):25453-63. Epub 2007 Jul 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17613531 17613531]
 [[Category: Homo sapiens]]
 [[Category: Insulysin]]
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 [[Category: zinc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:02:54 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:41:35 2008''