2jal: Difference between revisions

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Revision as of 18:39, 20 March 2008

File:2jal.gif

, resolution 1.90Å

Sites:

Ligands:

, and

Activity:

Beta-glucosidase, with EC number 3.2.1.21

Coordinates:

save as pdb, mmCIF, xml

BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOPHELLITOL

OverviewOverview

The structural basis for beta-glucosidase inhibition by cyclophellitol is demonstrated using X-ray crystallography, enzyme kinetics and mass spectrometry.

About this StructureAbout this Structure

2JAL is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

ReferenceReference

Structural basis for cyclophellitol inhibition of a beta-glucosidase., Gloster TM, Madsen R, Davies GJ, Org Biomol Chem. 2007 Feb 7;5(3):444-6. Epub 2006 Dec 14. PMID:17252125

Page seeded by OCA on Thu Mar 20 17:39:25 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2jal.gif|left|200px]]<br /><applet load="2jal" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2jal.gif|left|200px]]
-caption="2jal, resolution 1.90&Aring;" />
-'''BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOPHELLITOL'''<br />
+ {{Structure
+|PDB= 2jal |SIZE=350|CAPTION= <scene name='initialview01'>2jal</scene>, resolution 1.90&Aring;
+|SITE= <scene name='pdbsite=NUC:Ca+Binding+Site+For+Chain+B'>NUC</scene>
+|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=YLL:(1R,2S,3S,4S,5R,6R)-6-(HYDROXYMETHYL)CYCLOHEXANE-1,2,3,4,5-PENTOL'>YLL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21]
+|GENE=
+}}
+'''BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOPHELLITOL'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-JAL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=YLL:'>YLL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] Known structural/functional Site: <scene name='pdbsite=NUC:Ca+Binding+Site+For+Chain+B'>NUC</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAL OCA].
+JAL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAL OCA].
 ==Reference==
-Structural basis for cyclophellitol inhibition of a beta-glucosidase., Gloster TM, Madsen R, Davies GJ, Org Biomol Chem. 2007 Feb 7;5(3):444-6. Epub 2006 Dec 14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17252125 17252125]
+Structural basis for cyclophellitol inhibition of a beta-glucosidase., Gloster TM, Madsen R, Davies GJ, Org Biomol Chem. 2007 Feb 7;5(3):444-6. Epub 2006 Dec 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17252125 17252125]
 [[Category: Beta-glucosidase]]
 [[Category: Single protein]]
@@ Line 30: / Line 39: @@
 [[Category: polysaccharide degradation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:01:07 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:39:25 2008''