Sandbox Reserved 957: Difference between revisions
No edit summary |
No edit summary |
||
| Line 24: | Line 24: | ||
** <scene name='60/604476/Zn/1'>Zinc</scene> is critical for catalytic activity, but it isn't implied in the formation of the hydrophobic pocket. In fact, even if <scene name='60/604476/His653_his617/1'>the His617and 653</scene> are lost and so the Zn not bound, a massive addition of Manganese[4] in the medium allows a reactivation of catalysis.<br \> | ** <scene name='60/604476/Zn/1'>Zinc</scene> is critical for catalytic activity, but it isn't implied in the formation of the hydrophobic pocket. In fact, even if <scene name='60/604476/His653_his617/1'>the His617and 653</scene> are lost and so the Zn not bound, a massive addition of Manganese[4] in the medium allows a reactivation of catalysis.<br \> | ||
* W2 binds <scene name='60/604476/Mg_zn/1'>Zn and Mg</scene> [24],<br \> | * W2 binds <scene name='60/604476/Mg_zn/1'>Zn and Mg</scene> [24],<br \> | ||
* And there are 3 hydrogen bonds between 3 H2O and the conserved resides | * And there are 3 hydrogen bonds between 3 H2O and the conserved resides His657, Asp682 and His685 [24].<br \> | ||
Q site contains:<br \> | Q site contains:<br \> | ||