Sandbox Reserved 955: Difference between revisions
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'''Inhibitor structure''' | '''Inhibitor structure''' | ||
The sequence of the inhibitor JG-365 is Ac-Ser-Leu-Asn-Phe-psi[CH(OH)CH2N]-Pro-Ile-Val-OMe; the Ki is 0.24 nM. It's a protein with a length of 7 amino acid residues, composed of a C chain.<ref>http://www.rcsb.org/pdb/explore/explore.do?structureId=7hvp</ref> The inhibitor is positioned in a single orientation in the protease active site with the flaps folded directly over it, protecting the inhibitor from bulk solvent. | The sequence of the inhibitor JG-365 is<scene name='60/604474/Inhibitor/1'>Ac-Ser-Leu-Asn-Phe-psi[CH(OH)CH2N]-Pro-Ile-Val-OMe</scene>; the Ki is 0.24 nM. It's a protein with a length of 7 amino acid residues, composed of a C chain.<ref>http://www.rcsb.org/pdb/explore/explore.do?structureId=7hvp</ref> The inhibitor is positioned in a single orientation in the protease active site with the flaps folded directly over it, protecting the inhibitor from bulk solvent. | ||
'''HIV 1 protease structure''' | '''HIV 1 protease structure''' | ||