Sandbox Reserved 958: Difference between revisions
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< | <StructureSection load='4NYF' size='350' side='right' caption='Insert caption here' scene='60/604477/Structure/1'>{{Sandbox_ESBS}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
'''Dimer of HIV-1 integrase catalytic core domain''' is the active form of the '''3'-Processing''' reaction that occurs in patients cells suffering from '''AIDS'''. The catalytic core domain is just one of three parts composing the HIV-1 integrase. This enzyme performs mainly two specific reactions : the '''3'-processing''' and the '''integration of the viral DNA''' into the host genome. ''In vivo'' we can find this protein in several forms such as monomer, dimers and tetramers<ref name="Dells">PMID: 19091057</ref>. | '''Dimer of HIV-1 integrase catalytic core domain''' is the active form of the '''3'-Processing''' reaction that occurs in patients cells suffering from '''AIDS'''. The catalytic core domain is just one of three parts composing the HIV-1 integrase. This enzyme performs mainly two specific reactions : the '''3'-processing''' and the '''integration of the viral DNA''' into the host genome. ''In vivo'' we can find this protein in several forms such as monomer, dimers and tetramers<ref name="Dells">PMID: 19091057</ref>. | ||
==Biological role== | ==Biological role== | ||