2im0: Difference between revisions

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[[Image:2im0.jpg|left|200px]]<br /><applet load="2im0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2im0.jpg|left|200px]]
caption="2im0, resolution 2.25&Aring;" />
 
'''Crystal structure of poliovirus polymerase complexed with CTP and Mg2+'''<br />
{{Structure
|PDB= 2im0 |SIZE=350|CAPTION= <scene name='initialview01'>2im0</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=CTP:CYTIDINE-5'-TRIPHOSPHATE'>CTP</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48]
|GENE= 3D ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12080 Human poliovirus 1])
}}
 
'''Crystal structure of poliovirus polymerase complexed with CTP and Mg2+'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2IM0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_poliovirus_1 Human poliovirus 1] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=CTP:'>CTP</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IM0 OCA].  
2IM0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_poliovirus_1 Human poliovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IM0 OCA].  


==Reference==
==Reference==
Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions., Thompson AA, Albertini RA, Peersen OB, J Mol Biol. 2007 Mar 9;366(5):1459-74. Epub 2006 Dec 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17223130 17223130]
Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions., Thompson AA, Albertini RA, Peersen OB, J Mol Biol. 2007 Mar 9;366(5):1459-74. Epub 2006 Dec 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17223130 17223130]
[[Category: Human poliovirus 1]]
[[Category: Human poliovirus 1]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: stabilization]]
[[Category: stabilization]]


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