2i6z: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
[[Image:2i6z.jpg|left|200px]] | [[Image:2i6z.jpg|left|200px]] | ||
'''X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme''' | {{Structure | ||
|PDB= 2i6z |SIZE=350|CAPTION= <scene name='initialview01'>2i6z</scene>, resolution 1.90Å | |||
|SITE= <scene name='pdbsite=AC1:Cpt+Binding+Site+For+Residue+A+300'>AC1</scene>, <scene name='pdbsite=AC2:Cl+Binding+Site+For+Residue+A+500'>AC2</scene> and <scene name='pdbsite=AC3:Dms+Binding+Site+For+Residue+A+400'>AC3</scene> | |||
|LIGAND= <scene name='pdbligand=CPT:CIS-PLATINUM-(NH3)2'>CPT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=DMS:DIMETHYL SULFOXIDE'>DMS</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] | |||
|GENE= | |||
}} | |||
'''X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme''' | |||
==Overview== | ==Overview== | ||
Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
2I6Z is a [ | 2I6Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6Z OCA]. | ||
==Reference== | ==Reference== | ||
ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme., Casini A, Mastrobuoni G, Temperini C, Gabbiani C, Francese S, Moneti G, Supuran CT, Scozzafava A, Messori L, Chem Commun (Camb). 2007 Jan 14;(2):156-8. Epub 2006 Oct 26. PMID:[http:// | ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme., Casini A, Mastrobuoni G, Temperini C, Gabbiani C, Francese S, Moneti G, Supuran CT, Scozzafava A, Messori L, Chem Commun (Camb). 2007 Jan 14;(2):156-8. Epub 2006 Oct 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17180231 17180231] | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Lysozyme]] | [[Category: Lysozyme]] | ||
Line 20: | Line 29: | ||
[[Category: CPT]] | [[Category: CPT]] | ||
[[Category: DMS]] | [[Category: DMS]] | ||
[[Category: anticancer | [[Category: anticancer drug]] | ||
[[Category: cisplatin-lysozyme adduct]] | [[Category: cisplatin-lysozyme adduct]] | ||
[[Category: hydrolase]] | [[Category: hydrolase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:26:12 2008'' |