2hd6: Difference between revisions

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-[[Image:2hd6.gif|left|200px]]<br /><applet load="2hd6" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2hd6.gif|left|200px]]
-caption="2hd6, resolution 1.80&Aring;" />
-'''Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide.'''<br />
+ {{Structure
+|PDB= 2hd6 |SIZE=350|CAPTION= <scene name='initialview01'>2hd6</scene>, resolution 1.80&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MBO:MERCURIBENZOIC+ACID'>MBO</scene>, <scene name='pdbligand=BOS:N-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE'>BOS</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
+|GENE=
+}}
+'''Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide.'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-HD6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=MBO:'>MBO</scene>, <scene name='pdbligand=BOS:'>BOS</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD6 OCA].
+HD6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD6 OCA].
 ==Reference==
-Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX., De Simone G, Vitale RM, Di Fiore A, Pedone C, Scozzafava A, Montero JL, Winum JY, Supuran CT, J Med Chem. 2006 Sep 7;49(18):5544-51. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16942027 16942027]
+Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX., De Simone G, Vitale RM, Di Fiore A, Pedone C, Scozzafava A, Montero JL, Winum JY, Supuran CT, J Med Chem. 2006 Sep 7;49(18):5544-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16942027 16942027]
 [[Category: Carbonate dehydratase]]
 [[Category: Homo sapiens]]
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 [[Category: protein-inhibitor complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:40:37 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:15:32 2008''