4iy0: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4iy0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IY0 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4iy0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IY0 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iy2|4iy2]], [[4iy3|4iy3]], [[4iy4|4iy4]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iy2|4iy2]], [[4iy3|4iy3]], [[4iy4|4iy4]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CNNM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CNNM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4iy0 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4iy0 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Accardi, A | [[Category: Accardi, A]] | ||
[[Category: Corral-Rodriguez, M A | [[Category: Corral-Rodriguez, M A]] | ||
[[Category: Diercks, T | [[Category: Diercks, T]] | ||
[[Category: Encinar, J A | [[Category: Encinar, J A]] | ||
[[Category: Ereno-Orbea, J | [[Category: Ereno-Orbea, J]] | ||
[[Category: Gomez-Garcia, I | [[Category: Gomez-Garcia, I]] | ||
[[Category: Martinez-Cruz, L A | [[Category: Martinez-Cruz, L A]] | ||
[[Category: Muller, D | [[Category: Muller, D]] | ||
[[Category: Oyenarte, I | [[Category: Oyenarte, I]] | ||
[[Category: Spiwok, V | [[Category: Spiwok, V]] | ||
[[Category: Stuiver, M | [[Category: Stuiver, M]] | ||
[[Category: Terashima, H | [[Category: Terashima, H]] | ||
[[Category: Bateman domain]] | [[Category: Bateman domain]] | ||
[[Category: Cb]] | [[Category: Cb]] |
Revision as of 16:51, 4 January 2015
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
Structural highlights
Disease[CNNM2_HUMAN] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. Function[CNNM2_HUMAN] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). |
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