2gni: Difference between revisions

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OCA

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-[[Image:2gni.gif|left|200px]]<br /><applet load="2gni" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2gni.gif|left|200px]]
-caption="2gni, resolution 2.27&Aring;" />
-'''PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)'''<br />
+ {{Structure
+|PDB= 2gni |SIZE=350|CAPTION= <scene name='initialview01'>2gni</scene>, resolution 2.27&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=M77:5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE'>M77</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/cAMP-dependent_protein_kinase cAMP-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.11 2.7.11.11]
+|GENE= PRKACA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
+}}
+'''PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-GNI is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=M77:'>M77</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/cAMP-dependent_protein_kinase cAMP-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.11 2.7.11.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNI OCA].
+GNI is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNI OCA].
 ==Reference==
-Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity., Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D, J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16699172 16699172]
+Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity., Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D, J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16699172 16699172]
 [[Category: Bos taurus]]
 [[Category: Protein complex]]
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 [[Category: surrogate]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:33:28 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:06:48 2008''