2giq: Difference between revisions

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OCA

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-[[Image:2giq.jpg|left|200px]]<br /><applet load="2giq" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2giq.jpg|left|200px]]
-caption="2giq, resolution 1.65&Aring;" />
-'''Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-2 inhibitor'''<br />
+ {{Structure
+|PDB= 2giq |SIZE=350|CAPTION= <scene name='initialview01'>2giq</scene>, resolution 1.65&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NN2:1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BENZOTHIADIAZIN-3-YL)-6-FLUORO-4-HYDROXYQUINOLIN-2(1H)-ONE'>NN2</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48]
+|GENE= NS5B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10239 Viruses])
+}}
+'''Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-2 inhibitor'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-GIQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Viruses Viruses] with <scene name='pdbligand=NN2:'>NN2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIQ OCA].
+GIQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIQ OCA].
 ==Reference==
-Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus., Le Pogam S, Kang H, Harris SF, Leveque V, Giannetti AM, Ali S, Jiang WR, Rajyaguru S, Tavares G, Oshiro C, Hendricks T, Klumpp K, Symons J, Browner MF, Cammack N, Najera I, J Virol. 2006 Jun;80(12):6146-54. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16731953 16731953]
+Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus., Le Pogam S, Kang H, Harris SF, Leveque V, Giannetti AM, Ali S, Jiang WR, Rajyaguru S, Tavares G, Oshiro C, Hendricks T, Klumpp K, Symons J, Browner MF, Cammack N, Najera I, J Virol. 2006 Jun;80(12):6146-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16731953 16731953]
 [[Category: RNA-directed RNA polymerase]]
 [[Category: Single protein]]
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 [[Category: transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:32:02 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:05:14 2008''