2ghl: Difference between revisions

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OCA

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-[[Image:2ghl.gif|left|200px]]<br /><applet load="2ghl" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2ghl.gif|left|200px]]
-caption="2ghl, resolution 2.099&Aring;" />
-'''Mutant Mus Musculus P38 Kinase Domain in Complex with Inhibitor PG-874743'''<br />
+ {{Structure
+|PDB= 2ghl |SIZE=350|CAPTION= <scene name='initialview01'>2ghl</scene>, resolution 2.099&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=LIB:3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA'>LIB</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
+|GENE= Mapk14, Crk1, Csbp1, Csbp2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
+}}
+'''Mutant Mus Musculus P38 Kinase Domain in Complex with Inhibitor PG-874743'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-GHL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=LIB:'>LIB</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GHL OCA].
+GHL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GHL OCA].
 ==Reference==
-Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1., Brugel TA, Maier JA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Mekel MJ, Janusz MJ, Bioorg Med Chem Lett. 2006 Jul 1;16(13):3510-3. Epub 2006 May 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16632356 16632356]
+Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1., Brugel TA, Maier JA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Mekel MJ, Janusz MJ, Bioorg Med Chem Lett. 2006 Jul 1;16(13):3510-3. Epub 2006 May 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16632356 16632356]
 [[Category: Mus musculus]]
 [[Category: Non-specific serine/threonine protein kinase]]
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 [[Category: p38]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:31:50 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:04:46 2008''