2g8h: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
[[Image:2g8h.gif|left|200px]]<br /><applet load="2g8h" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2g8h.gif|left|200px]]
caption="2g8h, resolution 1.85&Aring;" />
 
'''B. halodurans RNase H catalytic domain D192N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site)'''<br />
{{Structure
|PDB= 2g8h |SIZE=350|CAPTION= <scene name='initialview01'>2g8h</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=VO4:VANADATE ION'>VO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4]
|GENE= rnhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=86665 Bacillus halodurans])
}}
 
'''B. halodurans RNase H catalytic domain D192N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site)'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
2G8H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=VO4:'>VO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8H OCA].  
2G8H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8H OCA].  


==Reference==
==Reference==
Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release., Nowotny M, Yang W, EMBO J. 2006 May 3;25(9):1924-33. Epub 2006 Apr 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16601679 16601679]
Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release., Nowotny M, Yang W, EMBO J. 2006 May 3;25(9):1924-33. Epub 2006 Apr 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16601679 16601679]
[[Category: Bacillus halodurans]]
[[Category: Bacillus halodurans]]
[[Category: Ribonuclease H]]
[[Category: Ribonuclease H]]
Line 22: Line 31:
[[Category: rnase h]]
[[Category: rnase h]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:29:10 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:01:38 2008''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA