2g6p: Difference between revisions
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[[Image:2g6p.gif|left|200px]] | [[Image:2g6p.gif|left|200px]] | ||
'''Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative''' | {{Structure | ||
|PDB= 2g6p |SIZE=350|CAPTION= <scene name='initialview01'>2g6p</scene>, resolution 1.90Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=HM2:5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE'>HM2</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] | |||
|GENE= METAP1, KIAA0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative''' | |||
==About this Structure== | ==About this Structure== | ||
2G6P is a [ | 2G6P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6P OCA]. | ||
==Reference== | ==Reference== | ||
Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases., Hu X, Addlagatta A, Matthews BW, Liu JO, Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3772-5. PMID:[http:// | Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases., Hu X, Addlagatta A, Matthews BW, Liu JO, Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3772-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16724298 16724298] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Methionyl aminopeptidase]] | [[Category: Methionyl aminopeptidase]] | ||
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[[Category: pyridinyl pyrimidine]] | [[Category: pyridinyl pyrimidine]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:01:06 2008'' | ||
Revision as of 18:01, 20 March 2008
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| , resolution 1.90Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , and | ||||||
| Gene: | METAP1, KIAA0094 (Homo sapiens) | ||||||
| Activity: | Methionyl aminopeptidase, with EC number 3.4.11.18 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative
About this StructureAbout this Structure
2G6P is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases., Hu X, Addlagatta A, Matthews BW, Liu JO, Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3772-5. PMID:16724298
Page seeded by OCA on Thu Mar 20 17:01:06 2008