2vuq: Difference between revisions
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<StructureSection load='2vuq' size='340' side='right' caption='[[2vuq]], [[Resolution|resolution]] 1.18Å' scene=''> | <StructureSection load='2vuq' size='340' side='right' caption='[[2vuq]], [[Resolution|resolution]] 1.18Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vuq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VUQ OCA]. | <table><tr><td colspan='2'>[[2vuq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VUQ FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vuq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vuq RCSB], [http://www.ebi.ac.uk/pdbsum/2vuq PDBsum]</span></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vuq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vuq RCSB], [http://www.ebi.ac.uk/pdbsum/2vuq PDBsum]</span></td></tr> | </table> | ||
<table> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Crystal structure of the human tRNAGly microhelix isoacceptor G9990 at 1.18A resolution.,Eichert A, Perbandt M, Schreiber A, Furste JP, Betzel C, Erdmann VA, Forster C Biochem Biophys Res Commun. 2009 Mar 13;380(3):503-7. Epub 2009 Jan 27. PMID:19284994<ref>PMID:19284994</ref> | Crystal structure of the human tRNAGly microhelix isoacceptor G9990 at 1.18A resolution.,Eichert A, Perbandt M, Schreiber A, Furste JP, Betzel C, Erdmann VA, Forster C Biochem Biophys Res Commun. 2009 Mar 13;380(3):503-7. Epub 2009 Jan 27. PMID:19284994<ref>PMID:19284994</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Betzel, C | [[Category: Betzel, C]] | ||
[[Category: Eichert, A | [[Category: Eichert, A]] | ||
[[Category: Erdmann, V A | [[Category: Erdmann, V A]] | ||
[[Category: Foerster, C | [[Category: Foerster, C]] | ||
[[Category: Fuerste, J P | [[Category: Fuerste, J P]] | ||
[[Category: Perbandt, M | [[Category: Perbandt, M]] | ||
[[Category: Schreiber, A | [[Category: Schreiber, A]] | ||
[[Category: Aminoacyl-trna-stem]] | [[Category: Aminoacyl-trna-stem]] | ||
[[Category: Class ii aminoacyl-trna / synthetase system]] | [[Category: Class ii aminoacyl-trna / synthetase system]] | ||
Revision as of 00:23, 4 January 2015
Crystal structure of a human tRNAGly acceptor stem microhelix (derived from the gene sequence DG9990) at 1.18 Angstroem resolutionCrystal structure of a human tRNAGly acceptor stem microhelix (derived from the gene sequence DG9990) at 1.18 Angstroem resolution
Structural highlights
Publication Abstract from PubMedThe tRNA(Gly)/Glycyl-tRNA synthetase system belongs to the so called 'class II' in which tRNA identity elements consist of relative few and simple motifs, as compared to 'class I' where the tRNA determinants are more complicated and spread over different parts of the tRNA, mostly including the anticodon. The determinants from 'class II' although, are located in the aminoacyl stem and sometimes include the discriminator base. There exist predominant structure differences for the Glycyl-tRNA-synthetases and for the tRNA(Gly) identity elements comparing eucaryotic/archaebacterial and eubacterial systems. We focus on comparative X-ray structure analysis of tRNA(Gly) acceptor stem microhelices from different organisms. Here, we report the X-ray structure of the human tRNA(Gly) microhelix isoacceptor G9990 at 1.18A resolution. Superposition experiments to another human tRNA(Gly) microhelix and a detailed comparison of the RNA hydration patterns show a great number of water molecules with identical positions in both RNAs. This is the first structure comparison of hydration layers from two isoacceptor tRNA microhelices with a naturally occurring base pair exchange. Crystal structure of the human tRNAGly microhelix isoacceptor G9990 at 1.18A resolution.,Eichert A, Perbandt M, Schreiber A, Furste JP, Betzel C, Erdmann VA, Forster C Biochem Biophys Res Commun. 2009 Mar 13;380(3):503-7. Epub 2009 Jan 27. PMID:19284994[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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