1jox: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jox]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JOX FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jox]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JOX FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jp0|1jp0]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jp0|1jp0]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jox RCSB], [http://www.ebi.ac.uk/pdbsum/1jox PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jox RCSB], [http://www.ebi.ac.uk/pdbsum/1jox PDBsum]</span></td></tr> | ||
<table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Doren, S R.Van | [[Category: Doren, S R.Van]] | ||
[[Category: Leeper, T C | [[Category: Leeper, T C]] | ||
[[Category: Schmidt, F J | [[Category: Schmidt, F J]] | ||
[[Category: Hairpin]] | [[Category: Hairpin]] | ||
[[Category: Residual dipolar coupling refinement]] | [[Category: Residual dipolar coupling refinement]] | ||
Revision as of 15:06, 2 January 2015
NMR Structure of the LP5.1 Hairpin from Bacillus RNase P RNA Refined with Residual Dipolar CouplingsNMR Structure of the LP5.1 Hairpin from Bacillus RNase P RNA Refined with Residual Dipolar Couplings
Structural highlights
Publication Abstract from PubMedLong-range interactions involving the P5.1 hairpin of Bacillus RNase P RNA are thought to form a structural truss to support RNA folding and activity. We determined the structure of this element by NMR and refined the structure using residual dipolar couplings from a sample weakly oriented in a dilute liquid crystalline mixture of polyethylene glycol and hexanol. Dipolar coupling refinement improved the global precision of the structure from 1.5 to 1.2 A (to the mean), revised the bend angle between segments of the P5.1 stem and corroborated the structure of the loop region. The UGAGAU hexaloop of P5.1 contains two stacks of bases on opposite sides of the loop, distinguishing it from GNRA tetraloops. The unusual conformation of the juxtaposed uracil residues within the hexaloop may explain their requirement in transactivation assays. Structure of the UGAGAU hexaloop that braces Bacillus RNase P for action.,Leeper TC, Martin MB, Kim H, Cox S, Semenchenko V, Schmidt FJ, Van Doren SR Nat Struct Biol. 2002 May;9(5):397-403. PMID:11927952[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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