2fzk: Difference between revisions
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[[Image:2fzk.gif|left|200px]]< | [[Image:2fzk.gif|left|200px]] | ||
'''The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.50 Resolution''' | {{Structure | ||
|PDB= 2fzk |SIZE=350|CAPTION= <scene name='initialview01'>2fzk</scene>, resolution 2.50Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=EOZ:3,5-BIS[(PHOSPHONOACETYL)AMINO]BENZOIC+ACID'>EOZ</scene> and <scene name='pdbligand=CTP:CYTIDINE-5'-TRIPHOSPHATE'>CTP</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Aspartate_carbamoyltransferase Aspartate carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.2 2.1.3.2] | |||
|GENE= PYRB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), PYRI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]) | |||
}} | |||
'''The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.50 Resolution''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2FZK is a [ | 2FZK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FZK OCA]. | ||
==Reference== | ==Reference== | ||
T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition., Heng S, Stieglitz KA, Eldo J, Xia J, Cardia JP, Kantrowitz ER, Biochemistry. 2006 Aug 22;45(33):10062-71. PMID:[http:// | T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition., Heng S, Stieglitz KA, Eldo J, Xia J, Cardia JP, Kantrowitz ER, Biochemistry. 2006 Aug 22;45(33):10062-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16906764 16906764] | ||
[[Category: Aspartate carbamoyltransferase]] | [[Category: Aspartate carbamoyltransferase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: ZN]] | [[Category: ZN]] | ||
[[Category: allosteric transition]] | [[Category: allosteric transition]] | ||
[[Category: | [[Category: inhibitor]] | ||
[[Category: xray | [[Category: xray structure]] | ||
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