Flotillin: Difference between revisions

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<scene name='60/607923/Mouse_flotillin/2'>mouse flot-2</scene>
<scene name='60/607923/Mouse_flotillin/2'>mouse flot-2</scene>


<StructureSection load='1win' size='340' side='right' caption='Caption for this structure' scene='60/607923/Mouse_flotillin_2/1'>
<StructureSection load='1win' size='340' side='right' caption='NMR structure of mouse flotillin 2 band 7 domain (PDB code [[1win]]).' scene='60/607923/Mouse_flotillin_2/1'>


Flotillins, also called reggie proteins, form a family of two ubiquitously expressed and highly conserved proteins, i.e., flotillin-1 and flotillin-2. Despite being products of different genes, both flotillins have a molecular weight of approximately 48 kDa and their sequences are quite similar (50% identity on mRNA level and 44% on protein level).
'''Flotillins''', also called reggie proteins, form a family of two ubiquitously expressed and highly conserved proteins, i.e., flotillin-1 and flotillin-2. Despite being products of different genes, both flotillins have a molecular weight of approximately 48 kDa and their sequences are quite similar (50% identity on mRNA level and 44% on protein level).
Flotillins are expressed in all mammals but they are also present in bacteria, plants, fungi and metazoans, but not in the budding yeast and C. elegant.
Flotillins are expressed in all mammals but they are also present in bacteria, plants, fungi and metazoans, but not in the budding yeast and C. elegant.


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Orly Spivak, Michal Harel, Joel L. Sussman