1ojk: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ojk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Humicola_insolens Humicola insolens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OJK FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ojk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Humicola_insolens Humicola insolens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OJK FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a39|1a39]], [[1dym|1dym]], [[1oji|1oji]], [[1ojj|1ojj]], [[2a39|2a39]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a39|1a39]], [[1dym|1dym]], [[1oji|1oji]], [[1ojj|1ojj]], [[2a39|2a39]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ojk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ojk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ojk RCSB], [http://www.ebi.ac.uk/pdbsum/1ojk PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ojk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ojk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ojk RCSB], [http://www.ebi.ac.uk/pdbsum/1ojk PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/GUN1_HUMIN GUN1_HUMIN]] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Cellulase]] | [[Category: Cellulase]] | ||
[[Category: Humicola insolens]] | [[Category: Humicola insolens]] | ||
[[Category: Brzozowski, A M | [[Category: Brzozowski, A M]] | ||
[[Category: Davies, G J | [[Category: Davies, G J]] | ||
[[Category: Ducros, V M.A | [[Category: Ducros, V M.A]] | ||
[[Category: Frandsen, T P | [[Category: Frandsen, T P]] | ||
[[Category: Ossowski, I Von | [[Category: Ossowski, I Von]] | ||
[[Category: Schulein, M | [[Category: Schulein, M]] | ||
[[Category: Tarling, C A | [[Category: Tarling, C A]] | ||
[[Category: Withers, S G | [[Category: Withers, S G]] | ||
[[Category: Zechel, D L | [[Category: Zechel, D L]] | ||
[[Category: Cellulose degradation]] | [[Category: Cellulose degradation]] | ||
[[Category: Glycosynthase]] | [[Category: Glycosynthase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||