2fmo: Difference between revisions

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-[[Image:2fmo.gif|left|200px]]<br /><applet load="2fmo" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2fmo.gif|left|200px]]
-caption="2fmo, resolution 2.25&Aring;" />
-'''Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase'''<br />
+ {{Structure
+|PDB= 2fmo |SIZE=350|CAPTION= <scene name='initialview01'>2fmo</scene>, resolution 2.25&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Methylenetetrahydrofolate_reductase_(NAD(P)H) Methylenetetrahydrofolate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.20 1.5.1.20]
+|GENE= metF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+}}
+'''Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-FMO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=FAD:'>FAD</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methylenetetrahydrofolate_reductase_(NAD(P)H) Methylenetetrahydrofolate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.20 1.5.1.20] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FMO OCA].
+FMO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FMO OCA].
 ==Reference==
-Structural perturbations in the Ala --&gt; Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation., Pejchal R, Campbell E, Guenther BD, Lennon BW, Matthews RG, Ludwig ML, Biochemistry. 2006 Apr 18;45(15):4808-18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16605249 16605249]
+Structural perturbations in the Ala --&gt; Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation., Pejchal R, Campbell E, Guenther BD, Lennon BW, Matthews RG, Ludwig ML, Biochemistry. 2006 Apr 18;45(15):4808-18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16605249 16605249]
 [[Category: Escherichia coli]]
 [[Category: Methylenetetrahydrofolate reductase (NAD(P)H)]]
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 [[Category: tim barrel]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:22:58 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:54:17 2008''