2fln: Difference between revisions
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[[Image:2fln.gif|left|200px]] | [[Image:2fln.gif|left|200px]] | ||
'''binary complex of catalytic core of human DNA polymerase iota with DNA (template A)''' | {{Structure | ||
|PDB= 2fln |SIZE=350|CAPTION= <scene name='initialview01'>2fln</scene>, resolution 2.50Å | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] | |||
|GENE= POLI, RAD30B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''binary complex of catalytic core of human DNA polymerase iota with DNA (template A)''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2FLN is a [ | 2FLN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLN OCA]. | ||
==Reference== | ==Reference== | ||
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site., Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK, Structure. 2006 Apr;14(4):749-55. PMID:[http:// | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site., Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK, Structure. 2006 Apr;14(4):749-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16615915 16615915] | ||
[[Category: DNA-directed DNA polymerase]] | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: dna polymerase]] | [[Category: dna polymerase]] | ||
[[Category: lesion bypass]] | [[Category: lesion bypass]] | ||
[[Category: template | [[Category: template some]] | ||
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