2fln: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
[[Image:2fln.gif|left|200px]]<br /><applet load="2fln" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fln.gif|left|200px]]
caption="2fln, resolution 2.50&Aring;" />
 
'''binary complex of catalytic core of human DNA polymerase iota with DNA (template A)'''<br />
{{Structure
|PDB= 2fln |SIZE=350|CAPTION= <scene name='initialview01'>2fln</scene>, resolution 2.50&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7]
|GENE= POLI, RAD30B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''binary complex of catalytic core of human DNA polymerase iota with DNA (template A)'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
2FLN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLN OCA].  
2FLN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLN OCA].  


==Reference==
==Reference==
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site., Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK, Structure. 2006 Apr;14(4):749-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16615915 16615915]
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site., Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK, Structure. 2006 Apr;14(4):749-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16615915 16615915]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 22: Line 31:
[[Category: dna polymerase]]
[[Category: dna polymerase]]
[[Category: lesion bypass]]
[[Category: lesion bypass]]
[[Category: template a]]
[[Category: template some]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:22:38 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:53:56 2008''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA