1a7g: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a7g RCSB], [http://www.ebi.ac.uk/pdbsum/1a7g PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a7g RCSB], [http://www.ebi.ac.uk/pdbsum/1a7g PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/VE2_HPV31 VE2_HPV31]] E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||