2aq2: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2apb|2apb]], [[2apf|2apf]], [[2apt|2apt]], [[2apv|2apv]], [[2apw|2apw]], [[2apx|2apx]], [[2aq1|2aq1]], [[2aq3|2aq3]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2apb|2apb]], [[2apf|2apf]], [[2apt|2apt]], [[2apv|2apv]], [[2apw|2apw]], [[2apx|2apx]], [[2aq1|2aq1]], [[2aq3|2aq3]]</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [http://www.ebi.ac.uk/pdbsum/2aq2 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [http://www.ebi.ac.uk/pdbsum/2aq2 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ENTC3_STAAU ENTC3_STAAU]] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Cho, S.]]
[[Category: Cho, S]]
[[Category: Guan, R.]]
[[Category: Guan, R]]
[[Category: Kerzic, M C.]]
[[Category: Kerzic, M C]]
[[Category: Kieke, M C.]]
[[Category: Kieke, M C]]
[[Category: Kranz, D M.]]
[[Category: Kranz, D M]]
[[Category: Mariuzza, R A.]]
[[Category: Mariuzza, R A]]
[[Category: Sundberg, E J.]]
[[Category: Sundberg, E J]]
[[Category: Swaminathan, C P.]]
[[Category: Swaminathan, C P]]
[[Category: Yang, J.]]
[[Category: Yang, J]]
[[Category: Complex structure]]
[[Category: Complex structure]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Staphlococcal enterotoxin c3]]
[[Category: Staphlococcal enterotoxin c3]]
[[Category: T-cell receptor v beta domain]]
[[Category: T-cell receptor v beta domain]]

Revision as of 23:15, 25 December 2014

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutantCrystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant

Structural highlights

2aq2 is a 2 chain structure with sequence from Mus musculus and Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:entC3 (Staphylococcus aureus)
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[ENTC3_STAAU] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2aq2, resolution 1.80Å

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