2eu2: Difference between revisions

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OCA

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-[[Image:2eu2.gif|left|200px]]<br /><applet load="2eu2" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2eu2.gif|left|200px]]
-caption="2eu2, resolution 1.15&Aring;" />
-'''Human Carbonic Anhydrase II in complex with novel inhibitors'''<br />
+ {{Structure
+|PDB= 2eu2 |SIZE=350|CAPTION= <scene name='initialview01'>2eu2</scene>, resolution 1.15&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=5DS:(R)-1-AMINO-1-[5-(DIMETHYLAMINO)-1,3,4-THIADIAZOL-2-YL]METHANESULFONAMIDE'>5DS</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
+|GENE= CA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Human Carbonic Anhydrase II in complex with novel inhibitors'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-EU2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=5DS:'>5DS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EU2 OCA].
+EU2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EU2 OCA].
 ==Reference==
-X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes., Fisher SZ, Govindasamy L, Boyle N, Agbandje-McKenna M, Silverman DN, Blackburn GM, McKenna R, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jul 1;62(Pt, 7):618-22. Epub 2006 Jun 10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16820676 16820676]
+X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes., Fisher SZ, Govindasamy L, Boyle N, Agbandje-McKenna M, Silverman DN, Blackburn GM, McKenna R, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jul 1;62(Pt, 7):618-22. Epub 2006 Jun 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16820676 16820676]
 [[Category: Carbonate dehydratase]]
 [[Category: Homo sapiens]]
@@ Line 28: / Line 37: @@
 [[Category: carbonic anhydrase ii proton transfer inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:14:31 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:44:22 2008''