3uci: Difference between revisions

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-[[Image:3uci.jpg|left|200px]]
+==Crystal structure of Rhodostomin ARLDDL mutant==
+<StructureSection load='3uci' size='340' side='right' caption='[[3uci]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3uci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UCI FirstGlance]. <br>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Calloselasma rhodostoma])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uci RCSB], [http://www.ebi.ac.uk/pdbsum/3uci PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
-{{STRUCTURE_3uci|  PDB=3uci  |  SCENE=  }}
+==See Also==
+*[[Disintegrin|Disintegrin]]
-===Crystal structure of Rhodostomin ARLDDL mutant===
+__TOC__
+</StructureSection>
-==About this Structure==
-[[3uci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCI OCA].
 [[Category: Calloselasma rhodostoma]]
-[[Category: Chang, Y S.]]
+[[Category: Chang, Y S]]
-[[Category: Chang, Y T.]]
+[[Category: Chang, Y T]]
-[[Category: Chen, C Y.]]
+[[Category: Chen, C Y]]
-[[Category: Chen, Y C.]]
+[[Category: Chen, Y C]]
-[[Category: Chuang, W J.]]
+[[Category: Chuang, W J]]
-[[Category: Huang, C H.]]
+[[Category: Huang, C H]]
-[[Category: Shiu, J H.]]
+[[Category: Shiu, J H]]
 [[Category: Disintegrin]]
 [[Category: Integrin alphavbeta3]]
 [[Category: Toxin]]