2epl: Difference between revisions

New page: left|200px<br /><applet load="2epl" size="350" color="white" frame="true" align="right" spinBox="true" caption="2epl, resolution 1.40Å" /> '''N-acetyl-B-D-glucosa...
 
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[[Image:2epl.jpg|left|200px]]<br /><applet load="2epl" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2epl.jpg|left|200px]]
caption="2epl, resolution 1.40&Aring;" />
 
'''N-acetyl-B-D-glucosaminidase (GCNA) from Streptococcus gordonii'''<br />
{{Structure
|PDB= 2epl |SIZE=350|CAPTION= <scene name='initialview01'>2epl</scene>, resolution 1.40&Aring;
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+X+740'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+X+741'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+X+742'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+X+743'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+X+744'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+X+745'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+X+746'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+X+747'>AC8</scene> and <scene name='pdbsite=AC9:Gol+Binding+Site+For+Residue+X+731'>AC9</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52]
|GENE= gcna ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1302 Streptococcus gordonii])
}}
 
'''N-acetyl-B-D-glucosaminidase (GCNA) from Streptococcus gordonii'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2EPL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_gordonii Streptococcus gordonii] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+X+740'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+X+741'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+X+742'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+X+743'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+X+744'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+X+745'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+X+746'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+X+747'>AC8</scene> and <scene name='pdbsite=AC9:Gol+Binding+Site+For+Residue+X+731'>AC9</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPL OCA].  
2EPL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_gordonii Streptococcus gordonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPL OCA].  


==Reference==
==Reference==
Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the endocarditis pathogen Streptococcus gordonii and its complex with the mechanism-based inhibitor NAG-thiazoline., Langley DB, Harty DW, Jacques NA, Hunter N, Guss JM, Collyer CA, J Mol Biol. 2008 Mar 14;377(1):104-16. Epub 2007 Sep 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18237743 18237743]
Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the endocarditis pathogen Streptococcus gordonii and its complex with the mechanism-based inhibitor NAG-thiazoline., Langley DB, Harty DW, Jacques NA, Hunter N, Guss JM, Collyer CA, J Mol Biol. 2008 Mar 14;377(1):104-16. Epub 2007 Sep 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18237743 18237743]
[[Category: Beta-N-acetylhexosaminidase]]
[[Category: Beta-N-acetylhexosaminidase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: glycoside hydrolase]]
[[Category: glycoside hydrolase]]


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