3odo: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3odo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3odo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3odo RCSB], [http://www.ebi.ac.uk/pdbsum/3odo PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3odo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3odo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3odo RCSB], [http://www.ebi.ac.uk/pdbsum/3odo PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/ARHG1_HUMAN ARHG1_HUMAN]] Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.<ref>PMID:8810315</ref> <ref>PMID:9641915</ref> <ref>PMID:9641916</ref> <ref>PMID:20098430</ref> | |||
== References == | |||
<references/> | |||
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</StructureSection> | </StructureSection> | ||