4op2: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4op2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OP2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4op2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OP2 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UX:(2S)-2-{4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]BIPHENYL-4-YL}-1,1,1-TRIFLUOROPROPAN-2-OL'>2UX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UX:(2S)-2-{4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]BIPHENYL-4-YL}-1,1,1-TRIFLUOROPROPAN-2-OL'>2UX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ohk|4ohk]], [[4ohm|4ohm]], [[4oho|4oho]], [[4ohp|4ohp]], [[4olh|4olh]], [[4op1|4op1]], [[4op3|4op3]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ohk|4ohk]], [[4ohm|4ohm]], [[4oho|4oho]], [[4ohp|4ohp]], [[4olh|4olh]], [[4op1|4op1]], [[4op3|4op3]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4op2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4op2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4op2 RCSB], [http://www.ebi.ac.uk/pdbsum/4op2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4op2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4op2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4op2 RCSB], [http://www.ebi.ac.uk/pdbsum/4op2 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN]] Inhibits glucokinase by forming an inactive complex with this enzyme. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Chmait, S | [[Category: Chmait, S]] | ||
[[Category: Jordan, S R | [[Category: Jordan, S R]] | ||
[[Category: Binds to and inhibits glucokinase]] | [[Category: Binds to and inhibits glucokinase]] | ||
[[Category: Carbohydrate binding protein-inhibitor complex]] | [[Category: Carbohydrate binding protein-inhibitor complex]] | ||
[[Category: Glucokinase]] | [[Category: Glucokinase]] | ||
[[Category: Sis domain containing protein]] | [[Category: Sis domain containing protein]] | ||
Revision as of 20:46, 25 December 2014
GKRP bound to AMG-0471 and Sorbitol-6-PhosphateGKRP bound to AMG-0471 and Sorbitol-6-Phosphate
Structural highlights
Function[GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme. |
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