3u10: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u10 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u10 RCSB], [http://www.ebi.ac.uk/pdbsum/3u10 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u10 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u10 RCSB], [http://www.ebi.ac.uk/pdbsum/3u10 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/HCN2_HUMAN HCN2_HUMAN]] Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity). | |||
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == |