3v16: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3v16]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus Staphylococcus aureus subsp. aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V16 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3v16]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus Staphylococcus aureus subsp. aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V16 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_diacylglycerol-lyase Phosphatidylinositol diacylglycerol-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.13 4.6.1.13] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_diacylglycerol-lyase Phosphatidylinositol diacylglycerol-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.13 4.6.1.13] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v16 RCSB], [http://www.ebi.ac.uk/pdbsum/3v16 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v16 RCSB], [http://www.ebi.ac.uk/pdbsum/3v16 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PLC_STAAE PLC_STAAE]] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable pi-Cation Latched Loop.,Goldstein R, Cheng J, Stec B, Roberts MF Biochemistry. 2012 Mar 27;51(12):2579-87. Epub 2012 Mar 16. PMID:22390775<ref>PMID:22390775</ref> | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable pi-Cation Latched Loop.,Goldstein R, Cheng J, Stec B, Roberts MF Biochemistry. 2012 Mar 27;51(12):2579-87. Epub 2012 Mar 16. PMID:22390775<ref>PMID:22390775</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
==See Also== | |||
*[[Phosphatidylinositol-specific phospholipase C|Phosphatidylinositol-specific phospholipase C]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Phosphatidylinositol diacylglycerol-lyase]] | [[Category: Phosphatidylinositol diacylglycerol-lyase]] | ||
[[Category: Staphylococcus aureus subsp. aureus]] | [[Category: Staphylococcus aureus subsp. aureus]] | ||
[[Category: Cheng, J | [[Category: Cheng, J]] | ||
[[Category: Goldstein, R I | [[Category: Goldstein, R I]] | ||
[[Category: Roberts, M F | [[Category: Roberts, M F]] | ||
[[Category: Stec, B | [[Category: Stec, B]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Phospholipase]] | [[Category: Phospholipase]] | ||
[[Category: Pi-cation]] | [[Category: Pi-cation]] | ||
[[Category: Tim barrel]] | [[Category: Tim barrel]] | ||