2eb3: Difference between revisions

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[[Image:2eb3.jpg|left|200px]]<br /><applet load="2eb3" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2eb3.jpg|left|200px]]
caption="2eb3, resolution 2.84&Aring;" />
 
'''Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP'''<br />
{{Structure
|PDB= 2eb3 |SIZE=350|CAPTION= <scene name='initialview01'>2eb3</scene>, resolution 2.84&Aring;
|SITE= <scene name='pdbsite=AC1:Anp+Binding+Site+For+Residue+A+2001'>AC1</scene>
|LIGAND= <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER'>ANP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1]
|GENE= EGFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP'''
 


==About this Structure==
==About this Structure==
2EB3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ANP:'>ANP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] Known structural/functional Site: <scene name='pdbsite=AC1:Anp+Binding+Site+For+Residue+A+2001'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EB3 OCA].  
2EB3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EB3 OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: ec 2 7.10 1]]
[[Category: ec 2 7.10 1]]
[[Category: kinase]]
[[Category: kinase]]
[[Category: national project on protein structural and functional analyses]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: nppsfa]]
[[Category: phosphorylation]]
[[Category: phosphorylation]]
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[[Category: riken structural genomics/proteomics initiative]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: transferase]]
[[Category: transferase]]
[[Category: transmembrane]]
[[Category: transmembrane]]
[[Category: tyrosine-protein kinase]]
[[Category: tyrosine-protein kinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:08:08 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:37:42 2008''

Revision as of 17:37, 20 March 2008

File:2eb3.jpg


PDB ID 2eb3

Drag the structure with the mouse to rotate
, resolution 2.84Å
Sites:
Ligands:
Gene: EGFR (Homo sapiens)
Activity: Receptor protein-tyrosine kinase, with EC number 2.7.10.1
Coordinates: save as pdb, mmCIF, xml



Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP


About this StructureAbout this Structure

2EB3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 16:37:42 2008

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