3aef: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aef OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aef RCSB], [http://www.ebi.ac.uk/pdbsum/3aef PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aef OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aef RCSB], [http://www.ebi.ac.uk/pdbsum/3aef PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/DHSD_PIG DHSD_PIG]] Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). [[http://www.uniprot.org/uniprot/DHSA_PIG DHSA_PIG]] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity). [[http://www.uniprot.org/uniprot/C560_PIG C560_PIG]] Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).<ref>PMID:17480203</ref>  [[http://www.uniprot.org/uniprot/DHSB_PIG DHSB_PIG]] Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
==See Also==
*[[Succinate Dehydrogenase|Succinate Dehydrogenase]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Harada, S.]]
[[Category: Harada, S]]
[[Category: Honma, T.]]
[[Category: Honma, T]]
[[Category: Inaoka, D K.]]
[[Category: Inaoka, D K]]
[[Category: Inoue, M.]]
[[Category: Inoue, M]]
[[Category: Kido, Y.]]
[[Category: Kido, Y]]
[[Category: Kita, K.]]
[[Category: Kita, K]]
[[Category: Mao, J.]]
[[Category: Mao, J]]
[[Category: Matsuoka, S.]]
[[Category: Matsuoka, S]]
[[Category: Omori, J.]]
[[Category: Omori, J]]
[[Category: Osanai, A.]]
[[Category: Osanai, A]]
[[Category: Sakamoto, K.]]
[[Category: Sakamoto, K]]
[[Category: Sasaki, T.]]
[[Category: Sasaki, T]]
[[Category: Shindo, M.]]
[[Category: Shindo, M]]
[[Category: Tanaka, A.]]
[[Category: Tanaka, A]]
[[Category: Electron transport]]
[[Category: Electron transport]]
[[Category: Fad-binding protein]]
[[Category: Fad-binding protein]]

Revision as of 18:24, 25 December 2014

Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocketCrystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket

Structural highlights

3aef is a 4 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , ,
Activity:Succinate dehydrogenase (ubiquinone), with EC number 1.3.5.1
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[DHSD_PIG] Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). [DHSA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity). [C560_PIG] Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).[1] [DHSB_PIG] Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

See Also

References

  1. Huo X, Su D, Wang A, Zhai Y, Xu J, Li X, Bartlam M, Sun F, Rao Z. Preliminary molecular characterization and crystallization of mitochondrial respiratory complex II from porcine heart. FEBS J. 2007 Mar;274(6):1524-9. PMID:17480203 doi:http://dx.doi.org/10.1111/j.1742-4658.2007.05698.x

3aef, resolution 2.80Å

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