2wrt: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wrt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wrt RCSB], [http://www.ebi.ac.uk/pdbsum/2wrt PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wrt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wrt RCSB], [http://www.ebi.ac.uk/pdbsum/2wrt PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/GST26_FASHE GST26_FASHE]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 17: | Line 19: | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | |||
*[[Glutathione S-transferase|Glutathione S-transferase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Fasciola hepatica]] | [[Category: Fasciola hepatica]] | ||
[[Category: Glutathione transferase]] | [[Category: Glutathione transferase]] | ||
[[Category: Brophy, P M | [[Category: Brophy, P M]] | ||
[[Category: Isupov, M N | [[Category: Isupov, M N]] | ||
[[Category: Lacourse, E J | [[Category: Lacourse, E J]] | ||
[[Category: Line, K | [[Category: Line, K]] | ||
[[Category: Littlechild, J A | [[Category: Littlechild, J A]] | ||
[[Category: Parasite]] | [[Category: Parasite]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Trematode]] | [[Category: Trematode]] | ||
Revision as of 18:07, 25 December 2014
THE 2.4 ANGSTROM STRUCTURE OF THE FASCIOLA HEPATICA MU CLASS GST, GST26THE 2.4 ANGSTROM STRUCTURE OF THE FASCIOLA HEPATICA MU CLASS GST, GST26
Structural highlights
Function[GST26_FASHE] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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