2dv0: Difference between revisions

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OCA

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-[[Image:2dv0.jpg|left|200px]]<br /><applet load="2dv0" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2dv0.jpg|left|200px]]
-caption="2dv0, resolution 1.62&Aring;" />
-'''Human Aldose Reductase complexed with zopolrestat after 6 days soaking(6days_soaked_2)'''<br />
+ {{Structure
+|PDB= 2dv0 |SIZE=350|CAPTION= <scene name='initialview01'>2dv0</scene>, resolution 1.62&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=ZST:3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID'>ZST</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
+|GENE=
+}}
+'''Human Aldose Reductase complexed with zopolrestat after 6 days soaking(6days_soaked_2)'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-DV0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=ZST:'>ZST</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DV0 OCA].
+DV0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DV0 OCA].
 ==Reference==
-Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions., Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G, J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16952371 16952371]
+Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions., Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G, J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16952371 16952371]
 [[Category: Aldehyde reductase]]
 [[Category: Homo sapiens]]
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 [[Category: tim barrel]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:02:58 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:31:56 2008''