4bqa: Difference between revisions

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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bqa RCSB], [http://www.ebi.ac.uk/pdbsum/4bqa PDBsum]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bqa RCSB], [http://www.ebi.ac.uk/pdbsum/4bqa PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ETS2_HUMAN ETS2_HUMAN]] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.<ref>PMID:11909962</ref> 
== References ==
<references/>
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</StructureSection>
</StructureSection>

Revision as of 16:30, 25 December 2014

Crystal structure of the ETS domain of human ETS2 in complex with DNACrystal structure of the ETS domain of human ETS2 in complex with DNA

Structural highlights

4bqa is a 9 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[ETS2_HUMAN] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.[1]

References

  1. Wasylyk C, Schlumberger SE, Criqui-Filipe P, Wasylyk B. Sp100 interacts with ETS-1 and stimulates its transcriptional activity. Mol Cell Biol. 2002 Apr;22(8):2687-702. PMID:11909962

4bqa, resolution 2.50Å

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