1iw2: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1iw2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1iw2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW2 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lf7|1lf7]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lf7|1lf7]]</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iw2 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw2 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iw2 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw2 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/CO8G_HUMAN CO8G_HUMAN]] C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ginell, S.]]
[[Category: Ginell, S]]
[[Category: Lebioda, L.]]
[[Category: Lebioda, L]]
[[Category: Minor, W.]]
[[Category: Minor, W]]
[[Category: Ortlund, E.]]
[[Category: Ortlund, E]]
[[Category: Parker, C L.]]
[[Category: Parker, C L]]
[[Category: Schreck, S F.]]
[[Category: Schreck, S F]]
[[Category: Sodetz, J M.]]
[[Category: Sodetz, J M]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Calyx]]
[[Category: Calyx]]

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