4qqe: Difference between revisions
No edit summary |
No edit summary |
||
| Line 6: | Line 6: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qqe RCSB], [http://www.ebi.ac.uk/pdbsum/4qqe PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qqe RCSB], [http://www.ebi.ac.uk/pdbsum/4qqe PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/WDR5_HUMAN WDR5_HUMAN]] Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.<ref>PMID:19556245</ref> <ref>PMID:19103755</ref> <ref>PMID:20018852</ref> <ref>PMID:16600877</ref> <ref>PMID:16829960</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Al-Awar, R | [[Category: Al-Awar, R]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C | [[Category: Bountra, C]] | ||
[[Category: Brown, P J | [[Category: Brown, P J]] | ||
[[Category: Dombrovski, L | [[Category: Dombrovski, L]] | ||
[[Category: Dong, A | [[Category: Dong, A]] | ||
[[Category: Edwards, A M | [[Category: Edwards, A M]] | ||
[[Category: Getlik, M | [[Category: Getlik, M]] | ||
[[Category: Poda, G | [[Category: Poda, G]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Schapira, M | [[Category: Schapira, M]] | ||
[[Category: Senisterra, G | [[Category: Senisterra, G]] | ||
[[Category: Smil, D | [[Category: Smil, D]] | ||
[[Category: Vedadi, M | [[Category: Vedadi, M]] | ||
[[Category: Wernimont, A | [[Category: Wernimont, A]] | ||
[[Category: Wu, H | [[Category: Wu, H]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Wdr5]] | [[Category: Wdr5]] | ||