2deb: Difference between revisions

← Older edit Newer edit →

Revision as of 17:26, 20 March 2008

File:2deb.jpg

, resolution 1.60Å

Ligands:

, and

Activity:

Carnitine O-palmitoyltransferase, with EC number 2.3.1.21

Coordinates:

save as pdb, mmCIF, xml

Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221

OverviewOverview

Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.

About this StructureAbout this Structure

2DEB is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

ReferenceReference

A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:16615901

Page seeded by OCA on Thu Mar 20 16:26:13 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2deb.jpg|left|200px]]<br /><applet load="2deb" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2deb.jpg|left|200px]]
-caption="2deb, resolution 1.60&Aring;" />
-'''Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221'''<br />
+ {{Structure
+|PDB= 2deb |SIZE=350|CAPTION= <scene name='initialview01'>2deb</scene>, resolution 1.60&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene> and <scene name='pdbligand=PLM:PALMITIC ACID'>PLM</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Carnitine_O-palmitoyltransferase Carnitine O-palmitoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.21 2.3.1.21]
+|GENE=
+}}
+'''Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-DEB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=BOG:'>BOG</scene>, <scene name='pdbligand=COA:'>COA</scene> and <scene name='pdbligand=PLM:'>PLM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carnitine_O-palmitoyltransferase Carnitine O-palmitoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.21 2.3.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEB OCA].
+DEB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEB OCA].
 ==Reference==
-A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16615901 16615901]
+A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16615901 16615901]
 [[Category: Carnitine O-palmitoyltransferase]]
 [[Category: Rattus norvegicus]]
@@ Line 29: / Line 38: @@
 [[Category: central six-stranded beta-sheet]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:57:58 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:26:13 2008''