3e7s: Difference between revisions

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 == Structural highlights ==
 <table><tr><td colspan='2'>[[3e7s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E7S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E7S FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AT2:ETHYL+4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE'>AT2</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AT2:ETHYL+4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE'>AT2</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
-<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e65|3e65]], [[3e67|3e67]], [[3e68|3e68]], [[3e6l|3e6l]], [[3e6n|3e6n]], [[3e6o|3e6o]], [[3e6t|3e6t]], [[3e7g|3e7g]], [[3e7i|3e7i]], [[3e7m|3e7m]], [[3e7t|3e7t]], [[3eah|3eah]], [[3eai|3eai]], [[3ebd|3ebd]], [[3ebf|3ebf]], [[3ej8|3ej8]]</td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e65|3e65]], [[3e67|3e67]], [[3e68|3e68]], [[3e6l|3e6l]], [[3e6n|3e6n]], [[3e6o|3e6o]], [[3e6t|3e6t]], [[3e7g|3e7g]], [[3e7i|3e7i]], [[3e7m|3e7m]], [[3e7t|3e7t]], [[3eah|3eah]], [[3eai|3eai]], [[3ebd|3ebd]], [[3ebf|3ebf]], [[3ej8|3ej8]]</td></tr>
-<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nos3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nos3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])</td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase Nitric-oxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase Nitric-oxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e7s RCSB], [http://www.ebi.ac.uk/pdbsum/3e7s PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e7s RCSB], [http://www.ebi.ac.uk/pdbsum/3e7s PDBsum]</span></td></tr>
-<table>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NOS3_BOVIN NOS3_BOVIN]] Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 [[Category: Bos taurus]]
 [[Category: Nitric-oxide synthase]]
-[[Category: Aberg, A.]]
+[[Category: Aberg, A]]
-[[Category: Andersson, G.]]
+[[Category: Andersson, G]]
-[[Category: Andrews, G.]]
+[[Category: Andrews, G]]
-[[Category: Arvai, A S.]]
+[[Category: Arvai, A S]]
-[[Category: Cheshire, D R.]]
+[[Category: Cheshire, D R]]
-[[Category: Connolly, S.]]
+[[Category: Connolly, S]]
-[[Category: Crane, B R.]]
+[[Category: Crane, B R]]
-[[Category: Garcin, E D.]]
+[[Category: Garcin, E D]]
-[[Category: Gensmantel, N P.]]
+[[Category: Gensmantel, N P]]
-[[Category: Getzoff, E D.]]
+[[Category: Getzoff, E D]]
-[[Category: Hamley, P J.]]
+[[Category: Hamley, P J]]
-[[Category: Kroeger, M D.]]
+[[Category: Kroeger, M D]]
-[[Category: Mallinder, P R.]]
+[[Category: Mallinder, P R]]
-[[Category: Mete, A.]]
+[[Category: Mete, A]]
-[[Category: Nicholls, D J.]]
+[[Category: Nicholls, D J]]
-[[Category: Rosenfeld, R J.]]
+[[Category: Rosenfeld, R J]]
-[[Category: St-Gallay, S A.]]
+[[Category: St-Gallay, S A]]
-[[Category: Stuehr, D J.]]
+[[Category: Stuehr, D J]]
-[[Category: Tainer, J A.]]
+[[Category: Tainer, J A]]
-[[Category: Tinker, A C.]]
+[[Category: Tinker, A C]]
-[[Category: Wallace, A V.]]
+[[Category: Wallace, A V]]
 [[Category: Fad]]
 [[Category: Fmn]]