2c66: Difference between revisions

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[[Image:2c66.gif|left|200px]]<br /><applet load="2c66" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2c66.gif|left|200px]]
caption="2c66, resolution 2.50&Aring;" />
 
'''MAO INHIBITION BY RASAGILINE ANALOGUES'''<br />
{{Structure
|PDB= 2c66 |SIZE=350|CAPTION= <scene name='initialview01'>2c66</scene>, resolution 2.50&Aring;
|SITE= <scene name='pdbsite=AC1:Rm2+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE DINUCLEOTIDE'>FAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Amine_oxidase_(flavin-containing) Amine oxidase (flavin-containing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4]
|GENE=
}}
 
'''MAO INHIBITION BY RASAGILINE ANALOGUES'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2C66 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FAD:'>FAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Amine_oxidase_(flavin-containing) Amine oxidase (flavin-containing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4] Known structural/functional Site: <scene name='pdbsite=AC1:Rm2+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C66 OCA].  
2C66 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C66 OCA].  


==Reference==
==Reference==
Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis., Binda C, Hubalek F, Li M, Herzig Y, Sterling J, Edmondson DE, Mattevi A, J Med Chem. 2005 Dec 29;48(26):8148-54. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16366596 16366596]
Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis., Binda C, Hubalek F, Li M, Herzig Y, Sterling J, Edmondson DE, Mattevi A, J Med Chem. 2005 Dec 29;48(26):8148-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16366596 16366596]
[[Category: Amine oxidase (flavin-containing)]]
[[Category: Amine oxidase (flavin-containing)]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: transmembrane]]
[[Category: transmembrane]]


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