1ni3: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ni3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ni3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ni3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ni3 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1ni3 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ni3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ni3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ni3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ni3 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1ni3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/YEI3_SCHPO YEI3_SCHPO]] Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity). Negatively regulates the G2/M transition in the cell cycle.<ref>PMID:22624651</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[GTP-binding protein|GTP-binding protein]]
*[[GTP-binding protein|GTP-binding protein]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 09:05, 25 December 2014

Structure of the Schizosaccharomyces pombe YchF GTPaseStructure of the Schizosaccharomyces pombe YchF GTPase

Structural highlights

1ni3 is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
NonStd Res:
Gene:SPAC27E2.03C (Schizosaccharomyces pombe)
Resources:FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Function

[YEI3_SCHPO] Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity). Negatively regulates the G2/M transition in the cell cycle.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Navarro FJ, Nurse P. A systematic screen reveals new elements acting at the G2/M cell cycle control. Genome Biol. 2012 May 24;13(5):R36. doi: 10.1186/gb-2012-13-5-r36. PMID:22624651 doi:http://dx.doi.org/10.1186/gb-2012-13-5-r36

1ni3, resolution 2.80Å

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